Pedigree

            /MANOLIS OR MANUEL (L) ANGELOS
        /KONSTANTINOS OR CONSTANTINE (L) EMPEROR ANGELOS
       |    \? (L) ?
    /ANDRONIKOS (L) DUKAS ANGELOS
   |   |    /ALEXIOS I (L) KOMNENOS EMPEROR BYZANTINE EMPIRE
   |    \THEODORA (L) KOMNENE
   |        \EIRENE IRENE IRINI (NOTES) (L) DUKAINA DUCENA
ISAAC II (L) ANGELUS EMPEROR BYZANTINE EMPIRE
   |    /THEODOROS (L) KASTAMONITES
    \EUPHROSYNE (L) KASTAMONITISSA

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